已證實內毒素水平超低
淋巴細胞分離液 (LSM) 可用于在體外從稀釋的全血中進行淋巴細胞的分離。其分離原理為密度梯度離心，利用全血中不同細胞類型比重的差異通過離心完成細胞的分離 (圖1)?？祵?nbsp; cellgro®淋巴分離液是一種無菌的等滲聚蔗糖和泛影酸鈉溶液，粘度低，在20℃下密度為1.077-1.080g/mL。
除了兩種現成的LSM產品，康寧可以根據您的需求，提供不同體積和包裝的產品定制。
特點
在FDA注冊的，經ISO13485:2003質量認證的cGMP車間進行生產
依據SAL 10 的水平無菌過濾，高質量標準
超低內毒素濃度 (＜0.25EU/ml@1:10稀釋）
眾多文獻引用
可定制不同規格
圖1：全血在LSM中離心后的各類細胞分布
訂購信息
參考文獻
1. Viral MHC class I inhibition evades CD8+T-cell effector responses in vivo but not CD8+T-cell priming. Maria D. Gainey et. al,PNAS, Nov 2012; 109: E3260 - E3267.
2. Ability of Mature Dendritic Cells to Interact with Regulatory T Cells Is Imprinted during Maturation. R Muthuswamy et. al., Cancer Res July 15, 200868; 5972
3. Positive feedback between PGE2 and COX2 redirects the differentiation of human dendritic cells toward stable myeloid-derived suppressor cells. Natasa Obermajer et. al., Blood, Nov 2011; 118: 5498 - 5505.
4. Delineation of antigen-specific and antigen-nonspecific CD8+ memory T-cell responses after cytokine-based cancer immunotherapy. Julia K. Tietze et.al, Blood, Mar 2012; 119: 3073 - 3083.
5. HLA-DR+ CD38+ CD4+ T Lymphocytes Have Elevated CCR5 Expression and Produce the Majority of R5-Tropic HIV-1 RNA In Vivo. Amie L. Meditzet. al., J.Virol., Oct 2011; 85: 10189 - 10200.
6. A Stimulation-Dependent Alternate Core Promoter Links Lymphotoxin α Expression with TGF-β1 and Fibroblast Growth Factor-7 Signaling in Primary Human T Cells. Brian H. Yokley et. al., J. Immunol., May 2013; 190: 4573 – 4584
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